Reakcja ludzkich komórek struktur jamy ustnej na różne materiały endodontyczne – badanie in vitro
In the resent years MTA has been extensively examined in dental science and numerous cytotoxicity and cell attachment investigations with various cell cultures showed better results with MTA in comparison to very many other dental materials [14]. Nowadays, the use of MTA can be assumed as gold standard for the closure of perforations defects or as root-end filling against which other materials need to be tested. The very good biocompatibility and bioactivity of MTA on PDL cells and osteoblasts are confirmed in the present study and are in fully accordance with the present knowledge about MTA [13, 15].
Whereas MTA is very well investigated also on human cell lines [14] to the best of our knowledge until today no data are published concerning the effect of Biodentine to human osteoblasts or PDL cells. Only Zhou et al. compared Biodentine and MTA in direct contact on human gingival fibroblasts. Both cements showed no significant differences in cell viabilities. The cells attached to and spread over both material surfaces [29].
When comparing Biodentine and its characteristic properties to other well established dental materials as Super EBA or glass ionomer cement one has no recourse to much experimental data in current literature. In an investigation of 2012 Al-Hiyasat et al. observed the quality of cellular attachment to various root-end filling materials and concluded that the best cellular attachment of fibroblasts can be observed on the surface of MTA, [...]
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