Reakcja ludzkich komórek struktur jamy ustnej
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Reakcja ludzkich komórek struktur jamy ustnej na różne materiały endodontyczne – badanie in vitro

Conclusion

ProRoot MTA and Biodentine showed no cytotoxicity and a good biocompatibility in direct contact with osteoblasts and PDL cells. Regarding cell survival and proliferation particularly of PDL cells Biodentine showed good results and can be considered as a well-tolerated endodontic material with stimulatory bioactive properties. Amalgam and especially composite resin might not provide an appropriate environment for osteoblasts and PDL cells.

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

All authors have contributed significantly to this work and contributed to the paper in the equal parts: SJ had the idea for the research and developed the concept, participated in the experiments, literature research and writing of the manuscript. JM performed the in vitro experiments and participated in the literature research and writing of the manuscript. JK participated in literature research, writing of the manuscript and carried out proofreading. TD participated in study development, literature research, writing of the manuscript and carried out proofreading. All authors read and approved the final manuscript.

Acknowledgement

We acknowledge support by Deutsche Forschungsgemeinschaft and Open Access Publication Fund of University of Muenster, Germany.

First publication in Head & [...]

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